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30 вересня

Дудка Є.А.
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Гаїна Н.І.
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Семків В.Б.
Табачнюк Н.В.
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Олієвська М.В.

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Клацик І.В.

The central research laboratory

Wednesday, 16 January 2013 14:17

The Central Research Laboratory  was established to  improve  methodical provision  and  to increase the efficiency of  scientific research in the field of  fundamental and clinical medicine according to the approval of the Academic Council of 30.08.2011 (proceedings № 1) beginning  from  January, 1, 2012 to establish a scientific  laboratory attached to  the Department of Pathological Physiology within the limits of  the total number of the University staff  (Rector’s  order  № 09-O of 02.12.2011).

The priority trend of work oftheCRL is to study the Pathophysiology of the kidneys and water-salt metabolism.

 The Head of the Central Research Laboratory  is  Doctor of Medical Sciences, Professor  Rogovyi Yu. Ye.

The structure of the CRL includes:

  • Laboratoryof pathophysiological and biochemical investigations (responsible – senior laboratory assistant Olenovych L.V.);
  • Operating theatre. Laboratory of the study of the renal function (responsible – Associate ProfessorDoroshko V.A.);
  • Laboratoryof  flaming photometry (responsible – Associate Professor Filipova L.O.);
  • vivarium (responsible  – Associate  Professor Dikal M.V.,  Assistant Slobodian K.V.).

The planned  research work of the Department of Pathological Physiology “Pathogenetic treatment of a  dysfunction of the  proximal section of the nephron  and syndrome of a  loss of sodium ions with urine, preventing disorders of the glomerular-tubular, tubular-tubular balance and the tubular-glomerular feedback under the conditions of the influence of  ecologically unfavourable factors”  is performed on the basis of  the Central  Research Laboratory.

The following research methods have been introduced on the basis of CRL:

  • pathophysiological (modeling of sublimated nephropathy, hemic and tissue hypoxia with the introduction of 2,4-dinitrophenol,  hepatorenal syndrome);
  • functional (a study of the  renal function under the conditions of water diuresis and loading with 3% sodium chloride specifying 45 indicators of renal function);
  • biochemical (a determination of malonic aldehyde, diene conjugates, superoxide dismutase activity, catalase,  glutationperoxidaze, protein by the method of Lowry, the  succinatedehydrogenase activity, the total, enzymatic, nonenzymaticfibrinolytic activity, unlimited proteolysis in case of lysis of azoalbumin,azocasein, azokol, a  determination of  the concentration of creatinine in urine and blood  plasma, protein in  urine);
  • chemical (an evalution of the concentration of sodium and potassium ions)
  • statistic (determining the arithmetic mean and standard error, reliability indicator, correlative, regressive, multivariative regressive and meta-analysis).

In 2012 the scientific staff of the CRL published  15  papers ( 2 monographs, 7 articles, 3 abstracts),receivedone positive solution for an invention, directed 2 requests  for innovation.

The following departments carry out researchwork  on the base of the CRL and  cooperate with it:

  • Bioorganic and Biologic Chemistry and Clinical Biochemistry   ( Associate Professor  Dikal M.V.)
  • Medical Biology, Genetics and Pharmaceutical Botanics   ( AssistantVepriuk Yu. M.)
  • Pharmacology ( Associate Professor  Philipets N.D., Assistant  Kopchuk T.G.)
  • Pharmacy  (Associate ProfessorGerush O. V.)
  • Internal Medicine, Clinical Pharmacology and Occupational Diseases ( Assistant  Zaliavska O.V.)
  • Medical and Pharmaceutical Chemistry (Assistant Velyka A.Ya.)
  • Physiology  Named after Ya.D. Kirshenblat  (Assistant  Gordienko V.V.)
  • Pathomorphology     (Professor  Davydenko  I . S.)
  • Surgery  (Professor Bilookyi V.V.)

Favourable conditions are created on the basis of the CRL  for completing theses  by the University staff members  and competitioners:

  • Doctoral thesis – Grytsiuk  M.I.,
  • Doctoral thesis – Dotsiuk L.G.,
  • Candidate’s dissertation – Nezboretsyi I.V.,
  • Candidate’s dissertation – Belyavskyi V.V.,
  • Candidate’s dissertation – Kolesnyk O.V.,
  • Candidate’s dissertation – Kopchuk T.G.,
  • Candidate’s dissertation – Slobodian K.V.,
  • Candidate’s dissertation – VepriukYu.M.